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‘Hombre y Lobo’ Mexican Street Style Tacos and Tequila Shop

Bienvenidos al Hombre y Lobo and GO BILLS!

Tequila cocktails and Mexican street style tacos are coming to downtown Buffalo in the form of Hombre y Lobo restaurant. 

Ryan DiFranco

Hombre y Lobo – or man and wolf in Spanish – will be dedicated to serving up super authentic Mexican street food. Co-owner Ryan DiFranco is a self-professed huge Bills fan, according to co-owner Isaac Domingue, who notes that it is the combination of Ryan’s love of Mexican fare, and a love for Buffalo and WNY, that is driving the concept. 

Ryan, who hails from Niagara Falls, is realizing his dream to return to his hometown to open Hombre y Lobo, where he will be able to redirect his cooking energies and passions that he acquired at his 9 year old flagship Denver restaurant, DiFranco’s Italian. The concept is born of Ryan’s “years of adventures in Mexico” that developed into a “a freaky obsession for street tacos.”

Isaac Domingue

With the help of Domingue, the two will open Hombre y Lobo at 149 Swan Street, in the former Black Button Distilling space. Domingue describes the taqueria as having “an electric interior, a family friendly environment, with homemade salsas, guac, and queso, for anyone looking for an escape to Mexico, who will come to call Hombre y Lobo home.”

As for the food?

“The food should ALWAYS speak for itself,” says DiFranco, who possesses a childlike excitement for tacos. “When you visit, you’ll be at the very next best thing to enjoying a taco and margarita on the beach in Mexico. Right here in the great Queen City.”

Former Black Button Distilling

Dates and details to remember:

The family Siberian Husky, Zander (who actually loves wearing a sombrero)

Grand Opening (Nov 5, 2021) – Join the Hombre y Lobo opening celebration and enjoy traditional street tacos, special tacos inspired by Buffalo, cocktails, and Latin music.

Industry Night (Mondays): Hombre y Lobo will be open Mondays “because we know what it’s like to be a hardworking member of the F&B industry.” Join Hombre y Lobo for marg, tequila, and taco specials, all night long, EVERY MONDAY.

Taco Tuesdays: (Tuesdays): Tacos deserve to be celebrated. Check out Hombre y Lobo for taco and cocktail specials on the day made for tacos.

Catering and Special Events: With a reservable private rooftop and capacity to cater offsite private parties, Hombre y Lobo has one of the best views in the city for a catered party and a planner (if desired) to make it the perfect event.

Authentic street tacos


Sunday: Closed Monday: 4-10PM Tuesday: 4-10PM Wednesday: Closed Thursday: 4-10PM Friday: 4-11PM Saturday: 4-11PM

For more information visit Hombre y Lobo in-person (grand opening is November 5 – see invite below), or visit the taqueria online.

Hombre y Lobo | 149 Swan Street | Buffalo, NY, 14203 | (716) 427-8703 | View menu | | Facebook | Instagram

Hours are M T Thur 4-10pm and Fri and Sat 4-11Pm.

Written by queenseyes


Newell Nussbaumer is 'queenseyes' - Eyes of the Queen City and Founder of Buffalo Rising. Co-founder Elmwood Avenue Festival of the Arts. Co-founder Powder Keg Festival that built the world's largest ice maze (Guinness Book of World Records). Instigator behind Emerald Beach at the Erie Basin Marina. Co-created Flurrious! winter festival. Co-creator of Rusty Chain Beer. Instigator behind Saturday Artisan Market (SAM) at Canalside, Buffalo Porchfest, and Paint vs. Paint. Founder of The Peddler retro and vintage market on Elmwood. Instigator behind Liberty Hound @ Canalside. Throws The Witches Ball at Statler City, the Hertel Alley Street Art Festival, and The Flutterby Festival.

Contact Newell Nussbaumer |

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